The Overview of Anti-PGL-1 and Anti-IDALLE L-ESAT 6 IgG Antibody Titers in Household Contact of Leprosy
Abstract
Household contact is a high-risk group for leprosy transmission. Household contact with a high titer of Glycolipid-1 phenolic possesses a higher risk to develop into leprosy. This study was an observational study. The subject of the study consisted of 95 household contacts living at the house of leprosy patient in Brondong Subdistrict, Lamongan Regency, East Java, Indonesia whom anti-phenolic Glycolipid-1 and anti-IDALLE L-ESAT 6 IgG antibody titers were measured. Measurement of anti-PGL-1 and anti-IDALLE L-ESAT 6 IgG levels used the enzyme linked immunosorbent assay (ELISA) technique. The mean levels of anti-PGL-1 IgG in all subjects were 134.54 units / mL (± 295.15) while the levels of anti-IDALLE L-ESAT 6 IgG were 408.61 units / mL. There was a significant positive relationship between levels of anti-PGL-1 IgG with anti-IDALLE L-ESAT 6 IgG (r = 0.247, p = 0.016) in the household contacts of leprosy patient.
Authors who publish with us agree to the following terms:
- Authors retain copyright and grant the publisher right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this proceeding.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the proceeding's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this proceeding.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories, pre-prints sites or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater dissemination of published work